The Botnar Institute of Immune Engineering (BIIE) proudly welcomes Prof. Emma Slack to its growing faculty. Prof. Slack holds a joint appointment as the Barclay-Williams Professor of Molecular Immunology at the Sir William Dunn School of Pathology within the University of Oxford.
Check out Baxiva, a biotechnology startup developing next-generation glycoconjugate vaccines to combat bacterial infections. Their mission is to address urgent global health needs by targeting pathogens with high clinical burden and rising antimicrobial resistance. Their lead program focuses on preventing urinary tract and invasive infections caused by Escherichia coli—the world’s leading cause of antibiotic-resistant infections.
Published in Science, a ground-breaking study by the Slack group reveals how combining vaccines with friendly bacteria can boost vaccination efficacy and potentially reduce reliance on antibiotics.
The Slack Lab warmly welcomes the laboratory for Mucosal Crosstalk. Their research is dedicated to understanding how the interactions between our microbiota, the intestinal epithelium, and immune cells in the intestinal mucosa maintain intestinal homeostasis, and how these interactions derail in disease. They employ interdisciplinary approaches at the interface of epithelial cell biology, microbiology and mucosal immunology in combination with versatile in vivo and in vitro models.
Interview from the Swiss Young Immunologist Society with Emma. Learn about Emma's passion for immunology, why Emma wanted to become a scientist and how diversity can benefit science.
We are delighted to announce that Professor Emma Slack is joining the Dunn School as the inaugural Barclay-Williams Professor of Molecular Immunology, in association with the Queen’s College.
Check out the latest video from the Botnar Research Centre for Child Health (BRCCH) introducing the multi-investigator research project led by Prof Emma Slack, ETH Zurich. Two very serious diseases of newborns – namely, inborn errors of metabolism and neonatal sepsis – currently have high mortality rates, long-term consequences for child development and limited treatment options. The project seeks to develop novel intervention strategies for these diseases using advancements in microbiota bioengineering.
Have a look at the video of the BRCCH introducing itself and its mission. It also includes some insights into the different research projects that have received funding in their multi-investigator project call in 2019.
Watch the SRF Puls coverage on our research on Corona virus vaccines.
Schädliche Darmbakterien mutieren und machen uns so das Leben schwer. Doch die Mutationen könnten ihnen auch zum Verhängnis werden.
Intestinal antibodies (IgA) can exert selective pressure on intestinal bacteria. Via oral vaccines, we can manipulate these selective pressures to force evolution of Salmonella that are impaired in transmitting disease. This new vaccination strategy could be used to prevent disease caused by antibiotic-resistant intestinal bacteria.
To celebrate the 50th anniversary of women's right to vote in Switzerland, the NCCR has launched a campagin introducing female researchers in Switzerland.
Watch the video and learn more about evolutionary trap vaccines.
Durch eine Schluckimpfung sollen Salmonellen bekämpft werden können. Die durch die Impfung gebildeten Antikörper können die Durchfallerreger während ihres Wachstums in Ketten legen und zu einer Art Floss zusammenbinden. Diese Klumpen können nicht in die Darmwand eindringen, was eine Entzündung unterdrückt. Und die gefangenen Salmonellen können untereinander kein genetisches Material mehr austauschen. Dies verhindert zum Beispiel, dass die Bakterien Antibiotikaresistenzen an Artgenossen weiterreichen.
Emma Wetter Slack receives the ETH Zurich Latsis Prize 2017 for her research on the development of oral vaccines against Salmonella in livestock. Watch the video to find out more.